|
|
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ <=> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+
|
1.3.1.70
Delta14-sterol reductase
|
–
|
BMK
|
| |
BRENDA:
BR29447
KEGG:
R05639
MetaCyc:
RXN66-306
|
|
|
|
4,4-dimethyl-5alpha-cholesta-8-en-3beta-ol + NADP+ <=> 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADPH + H+
|
1.3.1.72
Delta24-sterol reductase
|
–
|
MK
|
| |
BRENDA:
BS189403
KEGG:
R07499
MetaCyc:
RXN-20119
|
|
|
|
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + O2 + ferricytochrome_b5 + H+ <=> 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol + ferricytochrome_b5 + H2O
|
1.14.18.9
4alpha-methylsterol monooxygenase
|
–
|
K
|
| |
KEGG:
R07509
MetaCyc:
RXN-13712
|
|
|
|
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + O2 + NADH + H+ <=> 4beta-hydroxymethyl-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + H2O + NAD+
|
not assigned
|
–
|
M
|
| |
MetaCyc:
RXN-20112
|
|
|
|
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + O2 + NADH + H+ <=> 4beta-carboxy-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NAD+ + H2O
|
1.14.13.246
4beta-methylsterol monooxygenase
|
–
|
|
| |
MetaCyc:
RXN-20115
|
|
|
|
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + ferricytochrome_b5 + O2 + H+ <=> 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol + ferricytochrome_b5 + H2O
|
not assigned
|
–
|
M
|
| |
MetaCyc:
RXN66-310
|
|
|
|
lanosterol + reduced_flavodoxin + O2 <=> 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
| |
BRENDA:
BS386554
|
|
|
|
oxolanosterol + 2 reduced_ferredoxin_[iron-sulfur]_cluster + 2 H+ + O2 <=> 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + formate + 2 oxidized_ferredoxin + H2O
|
1.14.15.36
sterol 14alpha-demethylase (ferredoxin)
|
–
|
|
| |
BRENDA:
BS447959
|
|
|
|
lanosterol + 6 reduced_ferredoxin_[iron-sulfur]_cluster + 6 H+ + 3 O2 <=> 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + formate + 6 oxidized_ferredoxin + 4 H2O
|
1.14.15.36
sterol 14alpha-demethylase (ferredoxin)
|
–
|
|
| |
BRENDA:
BS447680
|
|
|
|
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + reduced_acceptor + O2 <=> 4-hydroxymethyl,4-methyl-zymosterol + acceptor + H2O
|
1.14.18.9
4alpha-methylsterol monooxygenase
|
–
|
|
| |
BRENDA:
BS386136
|
|
|
|
10-desmethyl-2,3-oxidosqualene <=> 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 26-normalabaricatriene
|
5.4.99.7
lanosterol synthase
|
–
|
|
| |
BRENDA:
BS427951
|
|
